Social isolation is deadly. Isolation and loneliness are to be avoided. I have found four warning signs that indicate loneliness is around the corner and, unless corrected will lead to a permanent and damaging condition. You may find others, but these give us a start. Your acquaintances are all your age You've stopped making friends You can't get up and out You are too inflexible. Have you noticed these signs? Start conversations now about how to avoid them.